This handbook consists of six core chapters: (1) systems engineering fundamentals discussion, (2) the NASA program/project life cycles, (3) systems engineering processes to get from a concept to a design, (4) systems engineering processes to get from a design to a final product,(5) crosscutting management processes in systems engineering,and (6) special topics relative to systems engineering. These core chapters are supplemented by appendices that provide outlines, examples, and further information to illustrate topics in the core chapters. The handbook makes extensive use of boxes and figures to define, refine, illustrate, and extend concepts in the core chapters without diverting the reader from the main information. The handbook provides top-level guidelines for good systems engineering practices; it is not intended in any way to be a directive. NASA/SP-2007-6105 Rev1 supersedes SP-6105, dated June 1995.